Fellow speaker,
If you are speaking to a business audience, find out the common letter abbreviations that your audience uses (i.e., CCCP, ACT, NCR, etc.) in their daily work. Then take those letters and express them in a way that shows your audience's frustrations. For instance, if you are speaking to computer programmers who often install a program called NCR that has a lot of installation problems, you could say, "and you know what NCR stands for: Not Computer Ready!"
Lettered,
Tim